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Micro-nano hierarchical structure on the substrate was fabricated by a hybrid approach including laser deposition, laser ablation and chemical dealloying. The structure consists of micro bumps with a width of 50 ?m and a height of 100 ?m, and nanoporous structures with a size of 70150 nm on the micro bumps. XRD and XPS results confirm that these hierarchical structures were made of Cu2O. For use in comparison, three additional structures with feature size in milliscale, microscale, and nanoscale were also prepared respectively by the proposed methods. Under visible light, the micro-nano structure exhibited the best performance of photodegradation. It is the result of the large specific