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The decline of oil production in Indonesia, which is primarily sourced from mature oil fields, has prompted the need for Enhanced Oil Recovery (EOR) technology to boost production. One of the promising chemical EOR method is surfactant injection to reduce the interfacial tension between oil and water. This study focuses on coreflood simulation to evaluate the performance of Alkyl Ethoxy Carboxylate (AEC) surfactants and the effect of adding Titanium Dioxide (TiO?) nanoparticles in efforts to increase oil recovery in sandstone. The primary objectives of this study are to investigate the changes in the relative permeability curve before and after the addition of AEC surfactant and TiO2 nanoparticles, to identify the possible physical mechanisms behind the application of AEC surfactant and TiO2 nanoparticles, and to determine optimal injection strategies through sensitivity and economic analysis. The research methodology includes data collection from previous laboratory experiments and numerical coreflood simulation using CMG STARS software. Coreflood matching indicates that the mechanisms during AEC surfactant injection include interfacial tension reduction, surfactant adsorption, and alteration of wettability toward more water-wet conditions. The addition of TiO? nanoparticles significantly enhances the wettability alteration effect, consistent with laboratory data showing a decrease in contact angle up to 8.8°. Also, the addition of TiO2 nanoparticle significantly decrease interfacial tension until two orde magnitude. Sensitivity analysis indicates that increasing injection volume from 0.1 PV to 0.5 PV and injection rate consistently enhances oil recovery. Based on technical and simple economic analysis, the most optimal injection strategy was identified in the 0.5 PV surfactant-nanoparticle injection scenario at a rate of 0.3 cm³/minute. This scenario successfully provided the largest additional oil recovery with the most efficient increase in production costs compared to other scenarios.