2016 JRNL PP Hyun Jae Kang - 1.pdf
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Terbatas  Irwan Sofiyan
» Gedung UPT Perpustakaan
Terbatas  Irwan Sofiyan
» Gedung UPT Perpustakaan
Photoacoustic (PA) images utilize pulsed lasers and
ultrasound transducers to visualize targets with higher optical
absorption than the surrounding medium. However, they are
susceptible to acoustic clutter and background noise artifacts
that obfuscate biomedical structures of interest. We investigated
three spatial-angular compounding methods to improve PA image
quality for biomedical applications, implemented by combining
multiple images acquired as an ultrasound probe was rotated
about the elevational axis with the laser beam and target fixed.
Compounding with conventional averaging was based on the pose
information of each PA image, while compounding with weighted
and selective averaging utilized both the pose and image content
information. Weighted-average compounding enhanced PA images
with the least distortion of signal size, particularly when there
were large (i.e., 2.5 mm and 7 ) perturbations from the initial
probe position. Selective-average compounding offered the best
improvement in image quality with up 181, 1665, and 1568 times
higher contrast, CNR, and SNR, respectively, compared to the
mean values of individual PA images. The three presented spatial
compounding methods have promising potential to enhance image
quality in multiple photoacoustic applications.