Perpustakaan Digital ITB

An evaluation of antitussive and expectorant/mucolitic activities of aquous extract of viper betle leaves has been carried out. Evaluation of antitussive effect was performed according to Charlier method, with some modification on it's detector using voltmeter and aerosol tusigen. The extract was able to decrease cough frequencies at dose of € 562.34 mg/kg, but not to cough intensity. Evaluation of respiratory tract mucus production effect was performed tracheotomically according to Rosbach method. The extract increased mucus production in respiratory tract at dose of € 316.23 mg/kg. Effect of extract on mucus consistency was evaluated using rheological method, in vitro, and it's showed that the higher the extract concentration, the lower the mucus viscocity. The experiment also conducted the antimicrobial effect on many strains of tracheal invection-induced bacteries. The results showed that the extract possessed antimicrobial activity against Hczerraophi L Lus influenza-e, Staphylococcus aureus and Streptococcus haemoLiticus beta.