Perpustakaan Digital ITB

Type 2 diabetes mellitus is a chronic disease with high prevalence both in geriatrics and non-geriatrics in the last decade. Higher contraindication in geriatrics is caused by the physiology changing, polypharmacy, decreasing compliance , and decreasing capability in self-medication. These factors affect on increasing risk of drug related problems (DRPs). The objetive of this study is to evaluate type and number of DRPs then analyze the difference of DRPs between geriatrics and non-geriatrics. This study was done retrospectively using medical records from type 2 diabetes mellitus patients who were hospitalized from November 2009 - Februari 2010. DRPs assessment was done based on four main pharmacological therapy of diabetes mellitus, include antihyperglicemics, antihypertensive, antihyperlipidemics, and antiplatelet aggregation drugs and then were analized the difference of DRPs between geriatrics and non-geritarics. Among 60 patients, DRPs were perfomed in 25 geriatrics and 27 non-geriatrics. DRPs in geriatrics were need for additional drug therapy 18, 18%; dose too high 5.45%, dose too low 3.64%, adverse drug reaction 29.09%, and drug interaction 43.64%. DRPs in non-geriatrics were need for additional drug therapy 29.17%; dose too high 4.17%; dose too low 10.42%; adverse drug reaction 20.83%, and drug interaction 39.58%. DRPs in geriatrics group were significantly higher than non-geriatric group, therefore geriatrics need more intensive preventing, monitoring and managing of DRPs.