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ANTIBIOTIC USE AND RESISTANT BACTERIAL PATTERN IN SURGICAL UNIT IN A HOSPITAL IN BANDUNG, INDONESIA

Penulis : Anne Marie Praveena S K [11614765]
Kontributor / Dosen Pembimbing :
  • Prof. I Ketut Adnyana, M.Si., Ph.D.
  • Dr. Pratiwi Wikaningtyas, S.Farm., Apt., M.Si.
  • dr. H. Uun Sumardi, Sp.PD-KPTI,KIC.
Jenis Koleksi : Tugas Akhir
Penerbit : Farmasi Klinik dan Komunitas
Fakultas : Sekolah Farmasi
Subjek :
Kata Kunci : antibiotik, bakteri, resistensi, ILO, ISKTK
Sumber :
Staf Input/Edit : yana mulyana   yana mulyana
File : 1 file
Tanggal Input : 18 Mar 2019

Antibiotics have been considered the most important factors fighting pathogenic bacteria. Nevertheless, some bacteria have developed a type of resistance against antibiotics these days due to the inappropriate use of antibiotics. As a consequence, they are able to live and even reproduce when exposed to antibiotics. Pharmacists play an important role in curbing the antibiotic resistance in patients in hospitals by limiting the inappropriate use of antibiotics. Besides that, pharmacists also play a role in counselling and educating patients and other health care professionals such as doctors, pharmacists and nurses. The research was carried out to investigate the bacterial pattern of antibiotic resistance of surgical site infection (SSI) and catheter-associated urinary tract infection (CAUTI) and to determine the appropriateness of antibiotics used in treatment in SSI and CAUTI in surgical unit. This research was in the form of descriptive analysis study carried out in Dr.Hasan Sadikin Government Hospital (RSHS). The specimens obtained during this research were pus from SSI patients and urine from CAUTI patients. The data was collected from patient medical records and laboratory results in the period August 2017 - June 2018. There were 14 subjects for SSI (from total 20 subjects) and 54 subjects (from total 179 subjects) for CAUTI. In SSI and CAUTI patients in RSHS, it turned out that E. coli (ESBL) was the most common bacterial pathogen resistant to 3rd generation cephalosporins such as ceftriaxone and cefotaxime at 57.1% for SSI and 40.7% for CAUTI. Resistant bacterial pattern to 3rd generation cephalosporins reported to be the highest using antibiotic susceptibility test. Chi-square test was used for CAUTI but not for SSI as the number of SSI patients was limited. It was used to determine the appropriate use of antibiotics with the bacterial isolates being tested. It was found out that there were more inappropriate antibiotics used for treatment in CAUTI patients that was 61.1% based on Chi-square test (p=0.000). For SSI patients, the inappropriate antibiotics used for treatment was 85.7%.

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