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The aviation sector confronts the imperative of decarbonization, necessitating the adoption of low-carbon propulsion technologies and alternative fuels. Hydrogen has emerged as a promising solution, offering the potential for sustainable and carbon-free aviation, either through combustion engines or fuel cells for electric motors. Unlike kerosene, the combustion of hydrogen generates no carbon dioxide emissions, presenting a disruptive innovation for reducing carbon footprints. This study evaluates whether the existing cabin safety requirements still adequacy and relevant to the certification specification requirements for liquid hydrogen-powered aircraft. The research employs a sequential analysis, delineating the content pertinent to liquid hydrogen for achieving cabin safety of CS-25 requirements in hydrogen-powered aircraft. This is accomplished through an analysis of fire risks associated with kerosene and liquid hydrogen concerning established cabin safety regulations for large aircraft. Utilizing data gathered from prior studies, in-flight and post-crash fire scenarios were examined for both fuels, employing analysis to unveil thematic similarities and differences. The findings indicate that certain existing requirements can be applied to liquid hydrogen-powered aircraft, on which cabin safety certification is based. However, these requirements may require updating to improve safety in the context of the potential risks inherent in the hydrogen environment, which may affect the increased flammability of materials in the cabin. In addition, new requirements are proposed to address potential hazards that are not currently accounted for in the existing regulations. An example is the requirement for ventilation of confined spaces onboard aircraft to prevent hydrogen accumulation in the event of a leak.