Perpustakaan Digital ITB

In elderly patients drug-related problems are prevalent and associated with changes in physiological functions therefore there is a relationship between aging and occurrence of DRPs. The aim of this study was to identify and assess the occurrence of DRPs in elderly patients admitted to Hasan Sadikin Hospital. An observational study involving 160 patients with GIT disorders, aged 60 years and over. A retrospective study was conducted by reviewing medical records available in a period of 2012-2013 to obtain demographic data, diseases, medication use, and potential DRPs that may occur in elderly patients who suffer gastrointestinal tract disorder, identification, analysis and recommendations of DRPs that related to gastrointestinal tract drugs. In total, 216 potential DRP were observed in the 160 patients who used gastrointestinal drugs with 16 cases (7.40%) of inappropriate drug, 4 cases (1.85%) of inappropriate drug form, 4 cases (1.85%) of inappropriate duplication of therapeutic group, Il cases (5.09%) of contraindication for drug, 1 case (0.46%) of no clear indication for drug use, 2 cases (0.92%) of no drug prescribed but clear indication. There is not identification of dose too low, long and short duration of treatment, but 14 cases (6.48%) of dose too high, inappropriate drug selection were the DRP most commonly observed. Seventy five percent of DRP occurring in 125 patients were drug—drug interactions in (16.66%) of pharmacodynamic drug interactions, and (59.25%) of pharmacokinetic drug interactions. Identification and analysis of DPRs showed that patients experienced potential DRPs that related to gastrointestinal drugs with (17.57%) of drug choice problem, (6.48%) of dosing problem, and (75.91 %) of drug interactions.