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This research addresses the challenges of water resource management in conflict-affected areas, with a case study focused on Gaza City. Gaza faces a severe water crisis due to over-extraction of groundwater, high levels of nitrate and chloride contamination, and limited natural water resources. The study provides a comprehensive evaluation of sustainable water supply alternatives, including seawater desalination using reverse osmosis technology, rainwater harvesting, and wastewater recycling, integrated with renewable energy solutions to minimize power consumption. Key findings highlight solutions to improve water quality and manage available quantities by enhancing water monitoring systems, reducing unaccounted-for water losses, and upgrading water infrastructure. The research also offers practical recommendations for developing comprehensive management policies based on sustainability principles such as Reduce, Reuse, and Recycle (3R) to achieve water security and ensure resource sustainability for future generations.