Perpustakaan Digital ITB

This study investigates antipsychotic regimen switching and dose adjustments among patients with schizophrenia, utilizing Kaplan-Meier curves to illustrate time dependent patterns. In a retrospective six-months long cohort study, 26.1% of patients experienced regimen switching, with atypical regimens (14.8%) transitioning faster than combination regimens (11.4%). Additionally, 61.4% of patients underwent notable antipsychotic dose adjustments, revealing a prescriber tendency to respond slowly to potential decreases in effectiveness. The findings highlight the stakes in tailoring treatments, with dose adjustments occurring within the initial two months, preceding regimen switching. This research offers valuable insights into the nuances of schizophrenia management, putting emphasis on the importance of individualized approaches to optimize treatment outcomes.