2020 EJRNL PP Christopher J. Chang -1.pdf
Terbatas Irwan Sofiyan
» ITB
Terbatas Irwan Sofiyan
» ITB
Sensors provide powerful tools and technologies to peer
into the natural world, enabling researchers to discover
and decipher new molecular phenomena through the design,
construction, and application of chemical probes. Indeed, the
invention of new sensors drives the ability to literally create
new types of experiments across a variety of different length
and time scales, bringing together chemists from core areas of
organic, inorganic, physical, biological, and analytical chemistry
together with biologists, physicists, and engineers in synergistic
ways. At its core, fundamental and applied research in chemical
sensors requires molecular-level selectivity in complex environments,
and in this context, the search for selectivity has
primarily focused on binding-based approaches derived from
molecular recognition, akin to the lock-and-key constructs that
endow enzymes and other biological systems with exquisite
specificity. Along these lines, the origins of supramolecular
host?guest chemistry have launched an entire field of
molecular sensors and molecular logic gates, and traditional
sensors use principles from this biomimetic and bioinspired
chemistry.