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2020 EJRNL PP Christopher J. Chang -1.pdf
Terbatas Irwan Sofiyan
» ITB

Sensors provide powerful tools and technologies to peer into the natural world, enabling researchers to discover and decipher new molecular phenomena through the design, construction, and application of chemical probes. Indeed, the invention of new sensors drives the ability to literally create new types of experiments across a variety of different length and time scales, bringing together chemists from core areas of organic, inorganic, physical, biological, and analytical chemistry together with biologists, physicists, and engineers in synergistic ways. At its core, fundamental and applied research in chemical sensors requires molecular-level selectivity in complex environments, and in this context, the search for selectivity has primarily focused on binding-based approaches derived from molecular recognition, akin to the lock-and-key constructs that endow enzymes and other biological systems with exquisite specificity. Along these lines, the origins of supramolecular host?guest chemistry have launched an entire field of molecular sensors and molecular logic gates, and traditional sensors use principles from this biomimetic and bioinspired chemistry.