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SEMICONDUCTING POLYMER NANOMATERIALS AS NEAR-INFRARED PHOTOACTIVATABLE PROTHERAPEUTICS FOR CANCER

Oleh   Jingchao Li [-]
Kontributor / Dosen Pembimbing : Kanyi Pu
Jenis Koleksi : Jurnal elektronik
Penerbit : Lain-lain
Fakultas :
Subjek :
Kata Kunci : Semiconducting Polymer Nanomaterials, Photoactivatable Protherapeutics, Cancer
Sumber : American Chemical Society (ACS)
Staf Input/Edit : Irwan Sofiyan  
File : 1 file
Tanggal Input : 2020-02-14 13:25:45

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2020 EJRNL PP Jingchao Li -1.pdf

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Cancer therapy is routinely performed in the clinic to cure cancer and control its progression, wherein therapeutic agents are generally used. To reduce side effects, protherapeutic agents that can be activated by overexpressed cancer biomarkers are under development. However, these agents still face certain extent of off-target activation in normal tissues, stimulating the interest to design external-stimuli activatable protherapeutics. In this regard, photoactivatable protherapeutic agents have been utilized for cancer treatments. However, because of the intrinsic features of photolabile moieties, most photoactivatable protherapeutic agents only respond to ultraviolet?visible light, limiting their in vivo applications. Thus, protherapeutic agents that can be activated by near-infrared (NIR) light with minimal phototoxicity and increased tissue penetration are highly desired....