2020 EJRNL PP Johannes L. Rockl -1.pdf
Terbatas Irwan Sofiyan
» ITB
Terbatas Irwan Sofiyan
» ITB
The importance of sustainable and green synthetic protocols for the
synthesis of fine chemicals has rapidly increased during the last decades in an effort to
reduce the use of fossil fuels and other finite resources. The replacement of common
reagents by electricity provides a cost- and atom-efficient, environmentally friendly, and
inherently safe access to novel synthetic routes. The selective formation of carbon?
carbon bonds between two distinct substrates is a crucial tool in organic chemistry. This
fundamental transformation enables access to a broad variety of complex molecular
architectures. In particular, the aryl?aryl bond formation has high significance for the
preparation of organic materials, drugs, and natural products. Besides well-known and
well-established reductive- and oxidative-reagent-mediated or transition-metal-catalyzed
coupling reactions, novel synthetic protocols have arisen, which require fewer steps than
conventional synthetic approaches.